Robust experimental designs & global communities

In this episode, Alice Limonciel and Vinicius Verri Hernandes explore how to design robust metabolomics and exposomics studies, strategies to make the most of past and future newborn screening samples, and the impact of global communities in the advancement of global science.

Vinicius Verri Hernandes

He is a Senior Scientist at The Global Exposomics & Biomonitoring Laboratory at the University of Vienna, Austria. Community-driven projects discussed in this episode include the exposome spectral library ExpoLib, the Cooperative Health Research in South Tyrol study and the CHRIS portal, the European infrastructure for human exposome (EIRENE) and its Austrian node Exposome Austria, the IHEN ambassador network and of course the soon-to-be Brazilian metabolomics community currently growing on the Portal Metabolômica Brasil and its Youtube channel with metabolomics resources in Portuguese.

Favorite metabolite
Cotinine
It is a product of nicotine metabolism that tells a lot about our lifestyle. Learn more in the episode!

Papers discussed in the episode
Verri Hernandes, Dordevic, Hantikainen et al. 2022 Metabolites | Age, Sex, Body Mass Index, Diet and Menopause Related Metabolites in a Large Homogeneous Alpine Cohort

Verri Hernandes et al. 2025 Environment International | Dried blood spots analysis for targeted and non-targeted exposomics

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Finally available – Alice’s first book
The STORY principle – A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop

Complement this episode with Alice’s perspective on the role of industry in the exposome community at the latest Global Exposome Forum Virtual Townhall panel discussion. To learn more about the relevance of dried blood spots, revisit our episodes on clinical metabolomics with Julie Courraud and physical markers of mental illness with Sabine Bahn.

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