Plant metabolism & community-driven software

In this episode, Alice Limonciel and Tomáš Pluskal discuss the beauty and the complexity of plant metabolism, sustainable ways to harness these molecules and pathways for medical applications, and the development of one of the most widely used softwares in metabolomics.
Tomáš Pluskal

Tomáš Pluskal

Dr. Tomáš Pluskal is leading the Biochemistry of Plant Specialized Metabolites research group at the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences.

Favorite metabolite
Aconitine, not only a poisonous metabolite synthesized by the Monkshood plant, but also a diterpene alkaloid with a chemical structure so intricate that humans still haven’t managed to synthesize it.

Papers discussed in this episode
Pluskal et al. Nature Plants 2019 The biosynthetic origin of psychoactive kavalactones in kava

Additional resources
Learn more about MZmine, the software co-developed by Tomáš Pluskal.

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Finally available – Alice’s first book
The STORY principle – A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop

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