Phenomics & Microbiome

In this episode, Alice Limonciel and Marc-Emmanuel Dumas discuss metabolites as the messengers of the microbiome towards the host, the added value of investigating multiple measures of the phenotype in the context of liver disease, and how machine learning and AI will impact the field in the near future.

Marc-Emmanuel Dumas

Marc-Emmanuel Dumas is Chair in Systems Medicine at the Department of Metabolism, Digestion and Reproduction of the Faculty of Medicine at Imperial College London in the UK and CNRS Director of Research and group leader at U1283/UMR8199 at the European Genomic Institute for Diabetes in Lille, France.

Learn more about the work of his team here.

Favorite metabolite
Phenylacetic acid (PAA)

Papers discussed in this episode
Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women
Lesley Hoyles, José-Manuel Fernández-Real, Massimo Federici et al. Nature Medicine. 2018 | https://doi.org/10.1038/s41591-018-0061-3

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Finally available – Alice’s first book
The STORY principle – A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop

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