Epidemiology & asthma

In this episode, Alice Limonciel and Rachel Kelly discuss the relevance of metabolomics to the field of epidemiology, the challenges in combining metabolomic studies for large meta-analyses , and the application of metabolomics to create metabotypes of asthma.

Rachel Kelly

Rachel Kelly is associate professor at the Brigham and Women’s Hospital in Boston MA (USA)

Favorite metabolite
sphingosine-1-phosphate

Papers we discussed in this episode
Metabo-Endotypes of Asthma Reveal Differences in Lung Function: Discovery and Validation in Two TOPMed Cohorts

Phenotypically driven subgroups of ASD display distinct metabolomic profiles

Activities in consortia
EnviroGenomarkers
COMETS – The consortium of metabolomics studies
COMETS analytics

On similarity network fusion

“Metabolomics is its own beast. You can’t treat it in the same way that you would genetics”

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Finally available – Alices first book
The STORY principle – A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1

Available on Amazon and the biocrates webshop

Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com

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