Democratizing healthcare & participatory medicine

In this episode, Alice Limonciel and Anne Bendt discuss why metabolomics is a disrupting technology in the field of clinical chemistry, the most critical steps needed for its implementation in the clinics and the fascinating lipidomes of bacteria.
Anne Bendt

Anne Bendt, PhD

She is Deputy Director and Principal Investigator at Singapore Lipidomics Incubator (SLING), Life Sciences Institute in Singapore.

Favorite metabolite
Tuberculostearic acid
A long-chain fatty acid produced by the bacteria responsible for tuberculosis, and investigated as a potential diagnostic biomarker of the disease and drug target. Learn more about tuberculostearic acid in the episode!

Papers discussed in this episode
On clinical metabolomics | Fux et al. 2024 A global perspective on the status of clinical metabolomics in laboratory medicine – a survey by the IFCC metabolomics working group Clin Chem Lab Med.

On PFAS and lipidomics | Narasimhan et al. 2024 Integrated analysis of per- and polyfluoroalkyl substances and plasma lipidomics profiles in multi-ethnic Asian subjects for exposome research Environmental Health

Additional resources
Learn more about the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Metabolomics working group and the International Lipidomics Society (ILS)-driven ceramides ring trial | Torte et al. 2024 Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards Nature Communications.

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Finally available – Alice’s first book
The STORY principle – A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop

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