Data quality & enabling research

In this episode, Alice Limonciel and Matthew Lewis discuss the pros and cons of establishing unifying principles on data quality in metabolomics, what drove the release of a decade's worth of work into the public domain and the role of industry in the scientific community.

Matthew Lewis

He is Vice President for Metabolomics & Lipidomics at Bruker, where he leads a team working on the development of solutions for small molecule bioanalysis. Matt also served as Chief Operations Officer at the National Phenome Center in the UK and has been a member of metabolomics quality assurance and quality control consortium (mQACC).

Favorite metabolite
Cysteine/Cystine
The sulfurous compounds that gave us biomarkers for one of the first inborn errors of metabolism described. Learn more in the episode!

Papers discussed in the episode
Lewis et al. 2022 Chemrxiv pre-print | An Open Platform for Large Scale LC-MS-Based Metabolomics

Sands et al. 2021 Anal Chem| Representing the Metabolome with High Fidelity: Range and Response as Quality Control Factors in LC-MS-Based Global Profiling

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Finally available – Alice’s first book
The STORY principle – A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop

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