Bacterial metabotypes & the medicine of tomorrow

In this episode, Alice Limonciel and Audrey Le Gouellec discuss how metabolomics provided a new understanding of cystic fibrosis, what metabolomics will bring to the medicine of tomorrow, and what we, as a community, need to do to get there.

Audrey Le Gouellec

Dr Audrey Le Gouellec is an Associate Professor and Hospital Practitioner in clinical biochemistry at the Faculty of Medicine, Université Grenoble Alpes and Centre Hospitalier Universitaire de Grenoble Alpes.
Learn more about her work at CHU Grenoble.
Discover the activities of the French Speaking Network for Metabolomics and Fluxomics (RFMF).

Favorite metabolite
Spermidine & hypusine

Papers discussed in this episode
Metabotypes of Pseudomonas aeruginosa Correlate with Antibiotic Resistance, Virulence and Clinical Outcome in Cystic Fibrosis Chronic Infections
Moyne et al. 2021 Metabolites https://doi.org/10.3390/metabo11020063

What clinical metabolomics will bring to the medicine of tomorrow

Le Gouellec et al. 2023 Mini review Frontiers in Analytical Science https://doi.org/10.3389/frans.2023.1142606
More about the Fibrotest discussed in this episode.

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Finally available – Alice’s first book
The STORY principle – A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop

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